Is it permissible for a woman afflicted with Marfan syndrome to conceive and bear children, given the significant danger to her life, reaching 90%, and her need for an abortion if she becomes pregnant to save her life, with only a 10% success rate?

If the situation is as described, it is not permissible for a woman to disobey the order of a trustworthy doctor to prevent pregnancy, due to the definite harm it would cause her. The Islamic Fiqh Academy and the Permanent Committee for Scholarly Research and Ifta have issued resolutions affirming the permissibility of contraception in cases of definite necessity.